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Description
Her3 His Tag Protein, MouseProduct Specification Species Mouse Synonyms Her3, ERBB3, LCCS2, MDA BF 1, MGC88033, c erbB3, erbB3 S, p180 ErbB3, p45 sErbB3, p85 sErbB3 Accession Q61526 Amino Acid Sequence Ser20 His641, with C terminal 10*His
Product Specification
| Species | Mouse |
| Synonyms | Her3, ERBB3, LCCS2, MDA-BF-1, MGC88033, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 |
| Accession | Q61526 |
| Amino Acid Sequence | Ser20-His641, with C-terminal 10*His SEMGNSQAVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVKNNGGNCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCNGRCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQTFCVRACPADKMEVDKNGLKMCEPCRGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPAEERLDIKYNRPLGECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEPREFVHEAHCFSCHPECQPMEGTSTCNGSGSDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCKGPELQDCLGQAEVLMSKPHGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 80-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Zhang N. et al. (2016) HER3/ErbB3, an emerging cancer therapeutic target. Acta Biochim Biophys Sin. 48(1): 39-48. |
Background
HER3 is a member of the HER (EGFR/ErbB) receptor family consisting of four closely related type 1 transmembrane receptors (EGFR, HER2, HER3, and HER4). HER receptors are part of a complex signaling network intertwined with the Ras/Raf/MAPK, PI3K/AKT, JAK/STAT, and PKC signaling pathways. Aberrant activation of the HER receptors and downstream signaling molecules tips the balance on cellular events, leading to various types of cancers. The HER3 protein is expressed in several types of tumors. That fact, together with the role of HER3 in promoting cell proliferation, implicate that targeting HER3 may have therapeutic relevance. Furthermore, expression and activation of HER3 has been linked to resistance to drugs that target other HER receptors such as agents that act on EGFR or HER2.
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4.9 ★★★★★
Based on 2492 reviews
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Product Reviews
★★★★★ 5
Fast shipping
Style: Ultra, Size: Small (2 Pack)
My Doxie’s Absolute Favorite Fetch Toy – Who Knew Baby Balls Could Be So Paw-some?
I bought these colorful baby balls as a simple toy for my little one, but my furry bay claimed them as his own from day one! These small, bouncy balls are perfect for little dogs – they’re lightweight and easy to grip in his mouth, keeping him entertained for hours. No squeakers or stuffing to destroy, just pure, durable fun. If your pup loves a good game of fetch or just batting things around, these “baby” balls are a steal. Highly recommend!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 27, 2026
★★★★★ 5
Great First Ball for a Puppy!
Style: Ultra, Size: Small (2 Pack), Style: Ultra, Size: Small (2 Pack)
Bought these small balls as the first real ball for my 3-month-old Boston Terrier puppy
He loves it!
Right away he picked one up and carried it around in his mouth all day
Perfect size for a tiny pup, bounces well, and he’s obsessed with fetching it
Holding up great so far during teething
Highly recommend for young puppies -simple, fun, and a big hit! 🐶❤️
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Reviewed in the United States on March 20, 2026
★★★★★ 5
Best Dog Ball!!
Style: Ultra, Size: Small (2 Pack), Style: Ultra, Size: Small (2 Pack)
Our pug has been obsessed with this ball since we gave it to her — she even slept with it. Somehow it’s still in one piece, which never happens. Easily the best dog ball we’ve bought.
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Reviewed in the United States on May 18, 2026
★★★★★ 5
Difficult to destroy. Bounce really high.
Style: Squeaker, Size: Small (2 Pack)
Bought as a gift for a friend's small dog who dismantles tennis balls. He loves them. I have many years of experience with the product (in a larger size) for my big dog. He always had one either in his mouth or near him. They are pretty much indestructible.
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Reviewed in the United States on May 13, 2026
★★★★★ 4
High quality, wish it was just a little smaller
Style: Squeaker, Size: Small (2 Pack)
Love these. My dogs would play ball all day if I let them. These are very durable and bouncy. Love that it’s washable. They would chew up the small “tennis” balls to pieces so I love that they can’t destroy these. My only criticism is I wish these were just a little smaller (like the size of the small Kong tennis balls). My dogs can carry it in their tiny mouths but they can’t get their mouth around it enough to chew it to get the squeaker to squeak, which is their favorite thing.
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Reviewed in the United States on January 5, 2026
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