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Description
PE Mouse Anti-Human CD206 Antibody (S-R575)Product Specification Host Mouse Antigen CD206 Synonyms Macrophage mannose receptor 1; MMR; C type lectin domain family 13 member D; C type lectin domain family 13 member D like; Human mannose receptor (hMR); Macrophage mannose receptor 1 like protein 1; CLEC13D; CLEC13DL; MRC1L1; MRC1 Location Endosome, Cell membrane Accession P22897 Clone Number S R575 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample GM CSF and IL
Product Specification
| Host | Mouse |
| Antigen | CD206 |
| Synonyms | Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human mannose receptor (hMR); Macrophage mannose receptor 1-like protein 1; CLEC13D; CLEC13DL; MRC1L1; MRC1 |
| Location | Endosome, Cell membrane |
| Accession | P22897 |
| Clone Number | S-R575 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | GM-CSF and IL-4 treated Human peripheral blood mononuclear cells |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | PE |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD206, also known as the mannose receptor (MRC1), is a highly glycosylated type I transmembrane protein primarily expressed on the surface of macrophages and dendritic cells. It plays a crucial role in the innate immune response by mediating the endocytosis and phagocytosis of various pathogens, including bacteria, fungi, and viruses, through its ability to bind to mannan-coated cell walls or envelopes. CD206 is a marker for alternatively activated M2 macrophages, which are characterized by their anti-inflammatory phenotype and are involved in wound healing and immune tolerance. In the context of cancer, tumor-associated macrophages often exhibit high levels of CD206, contributing to tumor progression by promoting immunosuppression, metastasis, and angiogenesis. This makes CD206 a potential target for cancer immunotherapy, as its activation can enhance both adaptive and innate antitumor immune responses.
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4.6 ★★★★★
Based on 1718 reviews
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Product Reviews
★★★★★ 4
Good quality and helpful even if your dog doesn’t use it yet
Color: Gray, Color: Gray
Still hoping my dog will decide to use this, but even if not, it’s serving a useful purpose. I keep pee pads down for accidents, and I started by placing this on top to encourage my dog to use it instead. Right now, I have it next to our end table to protect it, and it fits perfectly there. I may try putting a pad on top to help with the transition. The quality feels decent for the price—the plastic is thick enough, looks nice, and the top stays in place without being difficult to remove. It’s practical, easy to clean, and works well for what I needed.
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Reviewed in the United States on October 5, 2025
★★★★★ 5
The Best Interactive Dog Toy My Dogs Won’t Put Down!
Color: Blue
I have a Labrador and a Jack Russell and I bought this Qraxond interactive ball mainly for my Lab’s strong hunting instinct but I was absolutely blown away by how both dogs went crazy for it. This toy isn’t just fun it’s a total game changer for keeping pups entertained stimulated and out of trouble when I’m busy.
The ball arrived nicely packaged with clear easy to follow instructions. It comes with a USB C charging cable for the internal motor no wall adapter included but any standard USB plug works perfectly. The bright blue color is such a smart choice it stands out everywhere so I never lose it in the yard carpet or under furniture.
Operation is incredibly simple. The inner vibration module is held securely in the ball with heavy duty velcro. Inside a rubber core vibrates and makes the whole ball move and bounce unpredictably. There’s a protective plastic flap covering the charging port just press the button once for low mode again for high active mode and a third time to power off. Super intuitive for anyone to use.
The build quality is solid. While it’s not designed for aggressive chewers and the seller clearly states that which I really appreciate it holds up amazingly well for normal play. My dogs love shaking it tossing it and playing tug of war with me and each other and the toy hasn’t shown any signs of weakening. The reinforced fabric loops are stitched tightly and make it easy for dogs to grab shake and carry even my Lab has a blast tugging on it and the vibration keeps him distracted from pulling too hard.
The motion activated vibration works incredibly well. It’s highly sensitive so it activates as soon as your dog paws nudges or moves it then shuts off automatically when play stops to save battery. Both speed modes are a hit the low setting is gentle but engaging and the high setting gets them zooming around. The random movement triggers their natural prey drive so they can play independently for 10 to 20 minutes straight something my people focused standard poodle rarely does without human interaction. It’s fantastic mental stimulation that tires them out without me having to throw a ball a hundred times.
It’s truly versatile for all dog sizes and breeds you can’t get more different than a Labrador and a Jack Russell yet both adore it. I ended up buying a second one just to stop them from fighting over it! The soft padded outer cover is gentle on teeth and gums and since the instructions note to remove the inner core before cleaning the cover is clearly machine washable making cleanup a breeze.
Battery life is impressive it lasts through multiple play sessions before needing a charge and USB C charging is as convenient as charging a phone. At under $25 this toy offers incredible value way better than similar products I’ve tried that cost twice as much.
If you’re tired of boring toys that get ignored or need a way to keep your dog busy and mentally stimulated while you work or relax this Qraxond interactive ball is a must have. It’s durable fun easy to use and loved by every dog I’ve seen play with it. Highly highly recommend one of the best pet purchases I’ve ever made!
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Reviewed in the United States on April 12, 2026
★★★★★ 5
My dogs love this ball
Color: Blue
This interactive dog ball has been a huge hit with my doodles — Simba, Roxy, and Ozzy! The second I turn it on, they go crazy chasing it around the house. It keeps them entertained, active, and mentally stimulated, especially on rainy days when they can’t burn energy outside.
I love that it moves on its own and keeps them engaged without getting bored after 5 minutes like most toys. It’s durable enough for energetic dogs and rechargeable, which is a huge plus. Definitely worth it if you have playful pups that need extra stimulation and exercise!
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Reviewed in the United States on May 30, 2026
★★★★★ 4
The dog likes it, til her short attention span kicks in
Color: Green
This is an interesting toy.
Our little doodle really likes it when it starts up. She does lose interest after about 30 seconds. I think it's the pauses in-between the 10 second Normal or Crazy Bouncing Mode.
When she does play with it she is intense about it.
The loopy handles are very handy.
The company stands behind the product.
I would buy it again.
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Reviewed in the United States on May 9, 2026
★★★★★ 5
A favorite toy in our house!
Color: Blue
This is the best interactive ball ever! It combines two of my pups' favorite toys...a soccer ball and weighted moveable ball. Perfect independent toy! We've had it for a few weeks and I've only had to charge it once. Amazing battery life.
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Reviewed in the United States on May 17, 2026
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