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Ships within 48 hours · Estimated delivery Jul 12 - Jul 17
For Your Every Summer RSVP, with Code: SUMMER15
Description
IGFBP3 Recombinant rabbit mAb (SDT-086-63)Product Specification Host Rabbit Antigen IGFBP3 Synonyms Insulin like growth factor binding protein 3, IBP 3, IGF binding protein 3, IGFBP 3 Immunogen Recombinant Protein Location Secreted Accession P17936 Clone Number SDT 086 63 Antibody Type Rabbit mAb Application WB Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months
Product Specification
| Host | Rabbit |
| Antigen | IGFBP3 |
| Synonyms | Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3 |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | P17936 |
| Clone Number | SDT-086-63 |
| Antibody Type | Rabbit mAb |
| Application | WB |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
Background
Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF binding proteins. IGFBP-3 was first isolated, characterized, and quantitated in human plasma, in 1986. It has well-documented functions in the circulation, in the extracellular environment, and inside cells. It is the main IGF transport protein in the bloodstream, where it carries the growth factors predominantly in stable complexes that contain the binding protein, either IGF-1 or IGF-2, and a third protein called the acid-labile subunit or ALS. IGFBP-3 levels in human serum are, like IGF-1, dependent on growth hormone (GH); for example, serum IGFBP-3 is increased in acromegaly and low in GH-deficient children. However, IGFBP-3 gene expression in human liver is GH-independent. Because it is stabilized in human serum by forming complexes with IGF-1 and ALS, which are both GH-dependent, serum IGFBP-3 also appears regulated by GH. Its production by some non-hepatic tissues may also be directly GH-regulated. Immunoassays for serum IGFBP-3 are often used as part of the diagnosis of childhood GH-deficiency.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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4.1 ★★★★★
Based on 2412 reviews
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Product Reviews
★★★★★ 5
Awesome brackets!
Size: 8 Inch, Color: Black
These brackets are super durable and really nice looking! The price is amazing for what they give you too! Definitely will be buying more for other rooms!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 28, 2023
★★★★★ 5
Nice product
Size: 8 Inch, Color: Black
Very sturdy brackets. Easy to install.
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Reviewed in the United States on September 11, 2024
★★★★★ 5
Great Product
Size: 8 Inch, Color: Black, Size: 8 Inch, Color: Black
We needed extra storage options in a very small space. These brackets are good quality, several anchor options were included and they look great. These are 8 in. brackets and wooden boards are 8 in. wide and we cut to desired length.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 9, 2023
★★★★★ 5
Sleek and subtle
Size: 8 Inch, Color: Black
The work right side up and upside down. Just the look I was going for. I like them.
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Reviewed in the United States on April 2, 2024
★★★★★ 1
Do not recommend
Size: 12 Inch, Color: Black
Flimsy and poor quality. Hardware kept stripping screws.
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Reviewed in the United States on March 27, 2026
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