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Description
BOB-1 Recombinant Rabbit mAb (SDT-263-55)Product Specification Host Rabbit Antigen BOB 1 Synonyms POU2AF1, OBF 1, OCA B, OCT binding factor 1 Immunogen Synthetic Peptide Location Nucleus Accession Q16633 Clone Number SDT 263 55 Antibody Type Rabbit mAb Application WB, IHC P, ICC Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 125 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rabbit |
| Antigen | BOB-1 |
| Synonyms | POU2AF1, OBF-1, OCA-B, OCT-binding factor 1 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | Q16633 |
| Clone Number | SDT-263-55 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.125 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:500 | |
| WB | 1:5000 | |
| ICC | 1:125 |
Background
BOB-1 interacts with the sequence-specific DNA-binding POU transcription factors (named after the founding family members PIT1, OCT1/2, and UNC86), the ubiquitously expressed OCT1 (POU2F1) and lymphoid-specific OCT2 (POU2F2). As a transcriptional co-activator, BOB-1 itself does not bind DNA but is rather recruited into transcriptional regulation via interaction with DNA-bound POU-domain transcription factors OCT1 and OCT2. The POU-domain is a unique bipartite structure allowing DNA recognition with remarkable flexibility .
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