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Description
Human Desmoglein 3, His tagProduct Specification Species Human Synonyms 130 kDa pemphigus vulgaris antigen (PVA), Cadherin family member 6, DSG3, CDHF6 Accession P32926 Amino Acid Sequence Protein sequence(Q29432, Arg54 Val380, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | 130 kDa pemphigus vulgaris antigen (PVA), Cadherin family member 6, DSG3, CDHF6 |
| Accession | P32926 |
| Amino Acid Sequence | Protein sequence(Q29432, Arg54-Val380, with C-10*His) RGSNLTTHPLRNIKDLVYMGNITIGTPPQEFQVVFDTASSDLWVPSDFCTSPACSTHVRFRHLQSSTFRLTNKTFRITYGSGRMKGVVVHDTVRIGNLVSTDQPFGLSIEEYGFEGRIYDGVLGLNYPNISFSGAIPIFDKLKNQRAISEPVFAFYLSKDEREGSVVMFGGVDHRYYEGELNWVPLIQAGDWSVHMDRISIERKIIACSDGCKALVDTGTSDIVGPRRLVNNIHRLIGAIPRGSEHYVPCSEVNTLPSIVFTINGINYPVPGRAYILKDDRGRCYTTFQENRVSSSTETWYLGDVFLRLYFSVFDRGNDRIGLARAVGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:17.6kDa Actual:20-30kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the epidermis, and dominates in terms of expression on mucosal surfaces compared to Desmoglein-1. Desmoglein-3, along with Desmoglein-1, has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. The mucosal dominant form of pemphigus vulgaris only involves antibodies against Desmoglein-3 and causes mucosal erosions, but no skin lesions. Desmoglein-3 serves as a prognostic marker of Esophageal Squamous Cell Carcinoma (ESCC), and may even be involved in the progression of ESCC.
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4.9 ★★★★★
Based on 738 reviews
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Product Reviews
★★★★★ 5
True to size and great quality
Size: X-Large, Color: Colony Blue Melange
This shirt fits true to size. It is very soft and comfortable. The fabric is a thinner fabric that can be worn over dress shirts. The quality of the shirt seems to be very good. I have bought these pullovers in multiple colors, and they all seem to be consistent with the quality and size.
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Reviewed in the United States on January 8, 2026
★★★★★ 3
Received the wrong size
Size: X-Large, Color: Navy Melange
Seemed and looked like a decent quality shirt. A little lighter weight than I expected. I ordered an XL, but received a Large, which did not fit. Returned it and bought a similar shirt in a different brand.
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Reviewed in the United States on February 13, 2026
★★★★★ 5
Beautiful color
Size: Medium, Color: Red Melange
I loved the vibrant color of this shirt. The fabric is lightweight but not sun shirt/rash guard material. This will add a layer of warmth for seasons when the temperature fluctuates greatly during the course of the day. The sizing chart was accurate. My husband generally wears a medium but, based on the size chart, I bought him a large and it fit well.
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Reviewed in the United States on November 13, 2025
★★★★★ 5
Quality
Size: 3X-Large, Color: Dusty Rose Melange
Good fit
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Reviewed in the United States on May 17, 2026
★★★★★ 5
ASICS Gel Running Shoes – Comfortable, Lightweight & Perfect for Gym and Running
Size: 10.5 X-Wide, Color: Black/White, Size: 10.5 X-Wide, Color: Black/White
I recently tried a pair of ASICS Gel sneakers, and I’m really impressed. They are extremely comfortable, with great cushioning that makes a big difference during workouts. I’ve used them both at the gym and for running, and they perform very well in both situations.
The support is excellent, and they feel stable without being too heavy. I especially like how they absorb impact when running, which helps reduce stress on my feet and knees. They also have a nice fit and feel breathable, so my feet don’t get too hot.
Overall, I’m very happy with them. If you’re looking for comfortable and reliable sneakers for the gym and running, I would definitely recommend ASICS Gel shoes.
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Reviewed in the United States on April 20, 2026